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Letrozole Mechanism of Action and its Side Effects

buy letrozole learn side effects

Letrozole is a research liquid that functions as an aromatase inhibitor. Specifically it works by blocking estrogen from being produced using the enzyme aromatase. This research liquid is currently in testing for its properties to affects hormonally responsible breast cancer as well as its potential to decrease the risk of reoccurrence of cancer in animal test subjects.

Letrozole Mechanism of Action

In a process called aromatization, the enzyme aromatase is responsible for catalyzing the conversion of androgens into estrogen. This enzyme is located in female animal test subjects only; located in the tissue of the ovaries and breast tissue. Often, aromatase inhibitors are used for the treatment of cancers that can uses estrogen for growth and development. Decreasing the production of this hormone is supposed to cut off the cancerous cells ability to grow.

Letrozole works as an aromatase inhibitor, which means it inhibits the enzyme aromatase preventing the conversion of androgen to estrogen. With its ability to pass through cell membranes in fat cells, it is effective in altering estrogen levels in the breasts, starving cancerous tumors in animal test subjects.

Cancer Research with Letrozole

Hormones are chemical substances that are released into the bloodstream from a number of glands. Every hormone has a different effect on the cells it works on.

In cancers that are hormonally responsive, this hormone aids in the growth of the cancer and helps the development of more tumors. Hormonally responsive types of breast cancer have hormone receptor, which bind to the hormone. What Letrozole does is slow down the production of estrogen, to inhibit how many proteins can bind to the hormone. The tumors lose their source of growth, slowing down the rapid growth and potentially shrink.

Side Effects of Letrozole

Any type of peptide or research liquids is going to have a number of different side effects. Some side effects expected with Letrozole are:

  • Dizziness
  • Flushing
  • Headache
  • Nausea
  • Constipation
  • Bone, muscle, and joint pain
  • Gaining weight
  • Trouble sleeping
  • Hair loss
  • Numbness

Because this research liquid alters the levels of estrogen, as with most aromatase inhibitors there is an increased risk of developing osteoporosis and causing joint pain. To help prevent this, bisphosphonates are used these types of research liquids.

Research of Letrozole

Through a number of research studies, Letrozole has shown to have properties which prevent hormone positive breast cancers from growing in animal test subjects. It has also been shown to aid in ovulation problems. Due to the suppression of estrogen, the pituitary gland stimulates an increase of follicle stimulating hormone. Animals who suffer from POS or anovulation have shown to have increased ability to develop mature follicle and ovulation of eggs. Increased egg release helps it increase the rate of pregnancy in these animal test subjects.

Research liquids, such as Letrozole, and peptides are a vital part of the scientific community. They help us better understand the world and how to make strides towards an advanced community. Grindstone Labs knows how important your research is, which is why they offer quality research liquids at affordable price. With just a few clicks you can have peptides and research liquids delivered right to your door. These products are intended for laboratory use, only and should not be consumed by humans.

All products purchased from Grindstone Labs are for laboratory usage only.

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